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Bionomics Ltd: Deborah Rathjen shares their positive results from clinical trials in the areas of CNS and Oncology




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Video title: Bionomics Ltd: Deborah Rathjen shares their positive results from clinical trials in the areas of CNS and Oncology
Released on: December 14, 2011. © PharmaTelevision Ltd
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In this episode of PharmaTelevision News Review, Fintan Walton talks to Deborah Rathjen, CEO and Managing Director of Bionomics Ltd.
Full video transcripts are available with PharmaTelevision Premium Content. Click here to buy a subscription or sign up for a 14 day free trial.
Bionomics's promising data from clinical trials
Fintan Walton:
Hello and welcome to PharmaTelevision News Review here at AusBiotech's convention at Adelaide. On this show, I have Deborah Rathjen, who is CEO of a company called Bionomics , which is based here in Adelaide and is also chair of AusBiotech, welcome.
Deborah Rathjen:
Hi Fintan.
Fintan Walton:
So Deborah, as I said you are an Adelaide based biotechnology company, you've I understand in the last year you've got some new exciting data that's come out of your clinical trials, could you tell us little bit more about that?
Deborah Rathjen:
We have very exciting clinical data that's come from several trials this year most importantly in first up we had a clinical trial data coming from BNC210 a compound that's in development for anxiety depression and neurogenetic disorders such as Alzheimer's disease . We completed a couple of very exciting Phase Ib trials in those trials we gave people a panic attack and 210 was able to overcome the symptoms of panic attack when the subjects where on placebo they had much greater levels of panic both in terms of number of symptoms, intensity of those symptoms and when they are on 210 the recovery from the panic attack was faded which was just fantastic.The second trial we did showed that 210 got into the brain, the EEG recordings in the subjects on 210 showed that stimulated EEG activity that was consistent with anxiolytic activity in the absence of sedation so we through the trials also been able to show that 210 is remarkably free of side effects like sedation, memory impairment and so forth and some very promising clinical data.
Fintan Walton:
Right and obviously you gonna move now hopefully into Phase II up there is a plan?
Full video transcripts are available with PharmaTelevision Premium Content. Click here to buy a subscription or sign up for a 14 day free trial.
Fintan Walton
Dr Fintan Walton is the Founder and CEO of PharmaVentures . After completing his doctoral research on the genetics of cell proliferation at the University of Michigan(US)and Trinity College (Dublin, Ireland), Dr Walton gained broad commercial experience in biotechnology in management positions at Bass and Celltech plc (1982-1992).
Deborah Rathjen
Chief Executive Officer
At the time of recording this PTV interview Deborah Rathjen serves as Chief Executive Officer and Managing Director of Bionomics Limited. A seasoned biotech executive for almost 20 years, Dr Rathjen joined Bionomics Limited in June 2000 from Peptech Limited, where she was general manager of business development and licensing. Dr Rathjen was a co-inventor of Peptech 's TNF technology and leader of the company's successful defence of its key TNF patents against a legal challenge by BASF, providing Peptech with a strong commercial basis for licensing negotiations with BASF, Centocor and other companies with anti-TNF products. Dr Rathjen has significant experience in research, business development and licensing. Dr Rathjen is Chairperson of the AusBiotech Board, and is a member of the Higher Educatuion Council (SA Government). In 2004 Dr Rathjen was awarded the AusBiotech President's Medal for her significant contribution to the Australian biotechnology industry, in 2006 she received a Distinguished Alumni Award from Flinders University, in 2009 the BioSingapore Asia Pacific Woman Entrepreneur of the Year, and in 2010 Bio Innovation SA Industry Leader Award.
PharmaVentures
PharmaVentures is a corporate finance and transactions advisory firm that has served hundreds of clients worldwide in relation to their strategic deal making in the pharmaceutical, life science and healthcare sectors. Our key offerings include: Transactions / deal negotiations; Product / technology valuations; Deal term advice; Due diligence & expert reports; Strategy formulation; Alliance management; and Expert opinion for litigation/arbitration cases. PharmaVentures provides the global expertise to ensure our clients generate the highest possible return on investment from all their deal making activities. We have experience of all therapeutic areas and can offer advice on both product and technology commercialisation.
Bionomics Limited
Bionomics Limited is a productive drug discovery and development engine room focused on new treatments for cancer and serious disorders of the central nervous system . Through application of its proprietary technology platforms, MultiCore, Angene and ionX. Bionomics Limited has generated multiple drug candidates and targets in the therapeutics areas of cancer, anxiety, multiple sclerosis and epilepsy. The company has a strong out-license record in conjunction with its in-house development program which has seen two highly promising drugs enter clinical trials in the past two years. Background Bionomics was founded in 1999 by a group of Australia's leading healthcare researchers and initially established technology platforms in the genomics of epilepsy, angiogenesis and breast cancer. Using its CNS technologies, Bionomics became the first company in the world to develop a genetic test for Severe Myoclonic Epilepsy of Infants, a "catastrophic" form of epilepsy for which standard treatments are inappropriate. Using its Angene cancer target discovery platform, Bionomics has identified over 150 human genes implicated in angiogenesis - the growth in blood vessels that feed tumors. In 2005, the company achieved significant milestones in applying its technology to drug discovery. Through the acquisition of two companies, Neurofit Preclinical Research and Iliad Chemicals, it became the first company in Australia to establish a fully integrated small molecule drug discovery platform. The company now has proprietary technologies for each step in the drug discovery process: Target Discovery and Validation, Compound Libraries, High Throughput Screening, Medicinal Chemistry and Preclinical Development. The company has internal small molecule discovery programs operating in the following four areas: Angiogenesis and Vascular Targeting Agents (cancer); anxiety/ epilepsy and multiple sclerosis (CNS diseases). Bionomics has commercial partnerships with a number of leading healthcare companies including Merck Serono, GenMab, Athena Diagnostics, LabCorp, Perkin Elmer, and Genetic Technologies Ltd.